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What is Relapsing Polychondritis?


Also known as: Atrophic polychondritisand or Systemic chondromalacia, red ear syndrome.

 Relapsing Polychondritis
Chondritis means inflammation of cartilage.Relapsing polychondritis is a rare chronic disorder of the cartilage that is characterized by recurrent episodes of inflammation of the cartilage of various tissues of the body. The aetiology remains unknown.
Tissues containing cartilage that can become inflamed include the ears, nose, joints, spine, and windpipe (trachea). The eyes, heart, and blood vessels, which have a biochemical makeup similar to that of cartilage, can also be affected.
The term 'relapsing polychondritis' (RP) was first used in 19602 to describe a very rare disease which is characterised by recurrent episodes of inflammation of cartilaginous structures and other connective tissues, which may involve many organs. It can involve all types of cartilage including that of joints, tracheo-bronchial tree, ear and nose and connective tissues rich in proteoglycans, such as in the heart, eye, blood vessels and inner ear.

Causes

The cause of relapsing polychondritis is unknown. It is suspected that this condition is caused by "autoimmunity." Autoimmunity is characterized by a misdirected immune system. This results in inflammation in various tissues of the body.